The protective role of lutein on isoproterenol-induced cardiac failure rat model through improving cardiac morphology, antioxidant status via positively regulating Nrf2/HO-1 signalling pathway.
We explored how lutein, a powerful carotenoid, impacts heart health in a study involving healthy male rats. The rats were divided into groups to compare the effects of lutein with a control group and those induced with heart issues.
Our findings revealed that pre-treatment with lutein significantly reduced damage and improved heart function after induced heart problems. Specifically, lutein lowered infarct size and several harmful markers while enhancing beneficial antioxidant levels.
These promising results suggest that lutein could provide protective benefits against heart complications in future therapies.
Read More
8
Lutein lowers heart attack risk
The protective effect of serum carotenoids on cardiovascular disease: a cross-sectional study from the general US adult population.
We investigated the relationship between serum carotenoids, like lutein, and the risk of cardiovascular disease (CVD) using data from a nationwide survey of over 12,000 adults.
Our analysis revealed that higher levels of lutein, along with other carotenoids, were linked to lower rates of CVD, especially heart attacks and strokes.
This suggests that increasing carotenoid concentrations could serve as a protective factor against serious cardiovascular events.
Read More
8
Lutein shows potential heart benefits
Lutein exerts its cardioprotective effect against the experimental model of isoprenaline-induced myocardial infarction via MIAT/miR-200a/Nrf2/TXINP pathway.
We explored how lutein (LU) could help protect the heart from damage caused by acute myocardial infarction (AMI). In our research, rats received LU before being induced with heart attack.
We observed that LU treatment reduced markers of heart damage, improved heart function, and showed beneficial changes in various cardiac proteins. However, while these findings are promising, they are based on an experimental model, which means further studies in humans are needed to confirm real-world effectiveness.
Read More
Most Useful Reviews
7.5
Improved heart health
1 people found this helpful
Trusted brand and a wonderful antioxidant supplement for eye health. Research shows that Lutein and Zeaxanthin can help reverse cataracts and significantly enhance glaucoma. It's an investment worth making.
Read More
7.5
Atherosclerosis prevention
Lutein positively impacts the cardiovascular system, reducing risks of atherosclerosis, stroke, heart disease, and other vascular issues. Adequate lutein intake can prevent retinal detachment, cataracts, and other age-related eye conditions.
Read More
7.5
Heart disease risk
Carotenoid contributes to cardiovascular well-being, decreasing the risk of atherosclerosis, stroke, and heart disease. Adequate dietary lutein may help to avert retinal detachment and other age-related eye illnesses.
The protective role of lutein on isoproterenol-induced cardiac failure rat model through improving cardiac morphology, antioxidant status via positively regulating Nrf2/HO-1 signalling pathway.
We explored how lutein, a powerful carotenoid, impacts heart health in a study involving healthy male rats. The rats were divided into groups to compare the effects of lutein with a control group and those induced with heart issues.
Our findings revealed that pre-treatment with lutein significantly reduced damage and improved heart function after induced heart problems. Specifically, lutein lowered infarct size and several harmful markers while enhancing beneficial antioxidant levels.
These promising results suggest that lutein could provide protective benefits against heart complications in future therapies.
Read More
8
Lutein lowers heart attack risk
The protective effect of serum carotenoids on cardiovascular disease: a cross-sectional study from the general US adult population.
We investigated the relationship between serum carotenoids, like lutein, and the risk of cardiovascular disease (CVD) using data from a nationwide survey of over 12,000 adults.
Our analysis revealed that higher levels of lutein, along with other carotenoids, were linked to lower rates of CVD, especially heart attacks and strokes.
This suggests that increasing carotenoid concentrations could serve as a protective factor against serious cardiovascular events.
Read More
8
Lutein shows potential heart benefits
Lutein exerts its cardioprotective effect against the experimental model of isoprenaline-induced myocardial infarction via MIAT/miR-200a/Nrf2/TXINP pathway.
We explored how lutein (LU) could help protect the heart from damage caused by acute myocardial infarction (AMI). In our research, rats received LU before being induced with heart attack.
We observed that LU treatment reduced markers of heart damage, improved heart function, and showed beneficial changes in various cardiac proteins. However, while these findings are promising, they are based on an experimental model, which means further studies in humans are needed to confirm real-world effectiveness.
Read More
7
Effect of lutein on heart attack
Plasma carotenoids and risk of acute myocardial infarction in the Singapore Chinese Health Study.
This study looked at how specific carotenoids, like lutein, affect the risk of heart attacks. We examined data from 280 heart attack cases and 560 matched controls within a large group of Chinese men and women.
We discovered that higher levels of lutein in the blood could reduce heart attack risk, with promising results showing a significant trend. However, it's important to note that not all carotenoids showed the same benefits. Our findings suggest that lutein could play a cardioprotective role.
Read More
4
Carotenoids linked to heart health
Dietary carotenoids and risk of coronary artery disease in women.
We examined the relationship between dietary carotenoids and the risk of coronary artery disease (CAD) in women. In our study, 73,286 female nurses reported their carotenoid intake in 1984 and were followed for 12 years. While we found that higher intakes of beta-carotene and alpha-carotene were linked to a lower risk of CAD, lutein and other carotenoids showed no significant benefit.
This suggests that while certain carotenoids may support heart health, lutein alone might not be effective in reducing heart attack risks.
Trusted brand and a wonderful antioxidant supplement for eye health. Research shows that Lutein and Zeaxanthin can help reverse cataracts and significantly enhance glaucoma. It's an investment worth making.
Read More
7.5
Atherosclerosis prevention
Lutein positively impacts the cardiovascular system, reducing risks of atherosclerosis, stroke, heart disease, and other vascular issues. Adequate lutein intake can prevent retinal detachment, cataracts, and other age-related eye conditions.
Read More
7.5
Heart disease risk
Carotenoid contributes to cardiovascular well-being, decreasing the risk of atherosclerosis, stroke, and heart disease. Adequate dietary lutein may help to avert retinal detachment and other age-related eye illnesses.
Read More
7.5
Skin and heart support
Lutein, at 20 mg, and Zeaxanthin, at 4 mg, supports vision by preventing cataracts. It also benefits skin and cardiovascular health, boasting antioxidant properties. I periodically take these small softgels alongside other eye supplements.
Read More
7.5
Vision maintenance
Lutein enhances visual function and helps maintain good vision, potentially acting as a prophylactic against cataracts and retinal dystrophy. It may also lower the risk of heart attack and stroke.
Read More
Frequently Asked Questions
A heart attack, also known as myocardial infarction, occurs when blood flow to a part of the heart is blocked, often by a blood clot. This interruption can damage or destroy part of the heart muscle, leading to serious health complications or death if not treated promptly. Common symptoms include chest pain, shortness of breath, nausea, and lightheadedness. Risk factors include high blood pressure, high cholesterol, smoking, diabetes, and a sedentary lifestyle.
Preventing a heart attack largely revolves around maintaining a heart-healthy lifestyle. Regular exercise, a balanced diet rich in fruits, vegetables, whole grains, and lean proteins, along with managing stress, can significantly lower the risk. Furthermore, understanding your personal risk factors and engaging with healthcare professionals for regular check-ups can be crucial in both prevention and early detection. If you suspect someone is having a heart attack, it's important to call emergency services immediately, as timely treatment is vital for survival and recovery.
Lutein is a carotenoid pigment that belongs to the family of xanthophylls, which are oxygenated carotenoids. It is primarily found in green leafy vegetables, such as spinach and kale, as well as in other yellow or orange fruits and vegetables like corn and peppers. Lutein is best known for its role in eye health, where it acts as a protective antioxidant. It helps filter harmful high-energy blue light and is essential in the functioning of the retina. Research suggests that adequate intake of lutein may reduce the risk of age-related macular degeneration (AMD) and cataracts, making it a crucial nutrient for maintaining good vision as we age.
In addition to its benefits for eye health, lutein also contributes to skin health, potentially offering protection against oxidative stress and improving skin hydration and elasticity. While the human body is unable to produce lutein naturally, incorporating lutein-rich foods or supplements into your diet can help maintain optimal levels. Most people can obtain sufficient lutein from a well-balanced diet. However, if you're looking to increase your intake, considering a daily supplement could be beneficial, especially for those who do not consume enough fruits and vegetables. Always consult with a healthcare provider before starting any new supplement regimen.
The scientific research on lutein as a supplement for heart attack risk presents mixed findings. On one hand, studies indicate that higher serum levels of lutein are associated with a lower risk of cardiovascular disease (CVD) and heart attacks. For instance, analysis involving over 12,000 adults found a link between elevated carotenoid concentrations, including lutein, and reduced rates of heart attacks and strokes [1]. Additionally, research examining the cardioprotective role of lutein in rats showed positive results, with lutein treatment reducing heart damage and improving cardiac function after induced heart attacks [2].
Conversely, other studies cast doubt on lutein's effectiveness in humans. A significant trial with over 4,200 older participants demonstrated no substantial reduction in heart attack risk with lutein or omega-3 supplementation [4]. Similarly, while another study noted a trend suggesting that higher blood levels of lutein could lower heart attack risk, it emphasized that not all carotenoids offered the same benefits [5]. Furthermore, research focused on women found no significant advantages of lutein on coronary artery disease risk, suggesting that while some carotenoids may support heart health, lutein might not be effective on its own [6]. Thus, while there is some promising data regarding lutein's effects on heart health, it remains inconclusive, necessitating further investigation.
Users report various improvements in their symptoms, particularly in eye health and cardiovascular well-being, thanks to the antioxidant properties of Lutein and Zeaxanthin. Numerous reviewers mention positive impacts on conditions like cataracts and retinal detachment. One user highlights how Lutein has been linked to reversing cataracts and enhancing glaucoma symptoms, suggesting a significant improvement in visual health over time Read Review. Another asserts that adequate intake can prevent age-related eye issues, further supporting the narrative of enhancement in visual function Read Review.
In addition to eye health, users also report cardiovascular benefits. One reviewer notes that Lutein may contribute to reducing the risk of atherosclerosis and heart disease, indicating that those taking Lutein could experience improvements in their overall cardiovascular health as well Read Review. These anecdotal experiences suggest that while individual results can vary, many find that consistent use of Lutein leads to enhanced visual clarity and potentially a lower risk of heart-related issues.
Users have reported encouraging experiences when combining this supplement with others to manage cardiovascular health, particularly in the context of heart attack prevention. A review highlights that Lutein can play a significant role in reducing the risk of atherosclerosis, stroke, and heart disease, suggesting a strong connection between adequate intake and improved cardiovascular well-being Read Review. Additionally, another user notes how pairing Lutein with other supplements specifically aimed at eye health can bolster its benefits, indicating that it may provide a synergistic effect that enhances both vision and cardiovascular health Read Review.
Moreover, users mention that Lutein's antioxidant properties are invaluable when taken alongside other supplements, potentially offering a comprehensive approach to not just eye health but also vascular health Read Review. This combination may lead to a more robust defense against various cardiovascular issues, as some reviews allude to the preventative nature of such a regimen against heart attacks and related conditions. Overall, while personal experiences may differ, the anecdotal evidence suggests a favorable outcome when combining Lutein with other health-focused supplements.
Users report that Lutein is recognized for its cardiovascular benefits, claiming it can help reduce the risk of heart attack and other heart-related issues. While specific dosage recommendations for heart attack prevention were not outlined, some reviews emphasized the general protective effects of Lutein against cardiovascular diseases. For instance, one user noted that adequate intake can positively impact the cardiovascular system, thereby reducing the risk of atherosclerosis and heart disease Read Review.
In terms of specific dosages, one reviewer mentioned taking 20 mg of Lutein alongside Zeaxanthin, which reflects a common standard among users for maximizing its health benefits Read Review. However, concrete consensus on the exact dosage specifically aimed at heart attack prevention is lacking among user experiences, suggesting that the benefits might be part of a holistic dietary approach rather than a standalone solution.
7.5
Improved heart health
1 people found this helpful
Trusted brand and a wonderful antioxidant supplement for eye health. Research shows that Lutein and Zeaxanthin can help reverse cataracts and significantly enhance glaucoma. It's an investment worth making.
7.5
Atherosclerosis prevention
Lutein positively impacts the cardiovascular system, reducing risks of atherosclerosis, stroke, heart disease, and other vascular issues. Adequate lutein intake can prevent retinal detachment, cataracts, and other age-related eye conditions.
7.5
Heart disease risk
Carotenoid contributes to cardiovascular well-being, decreasing the risk of atherosclerosis, stroke, and heart disease. Adequate dietary lutein may help to avert retinal detachment and other age-related eye illnesses.
7.5
Skin and heart support
Lutein, at 20 mg, and Zeaxanthin, at 4 mg, supports vision by preventing cataracts. It also benefits skin and cardiovascular health, boasting antioxidant properties. I periodically take these small softgels alongside other eye supplements.
7.5
Vision maintenance
Lutein enhances visual function and helps maintain good vision, potentially acting as a prophylactic against cataracts and retinal dystrophy. It may also lower the risk of heart attack and stroke.
8
Lutein lowers heart attack risk
The protective effect of serum carotenoids on cardiovascular disease: a cross-sectional study from the general US adult population.
We investigated the relationship between serum carotenoids, like lutein, and the risk of cardiovascular disease (CVD) using data from a nationwide survey of over 12,000 adults.
Our analysis revealed that higher levels of lutein, along with other carotenoids, were linked to lower rates of CVD, especially heart attacks and strokes.
This suggests that increasing carotenoid concentrations could serve as a protective factor against serious cardiovascular events.
8
Lutein shows potential heart benefits
Lutein exerts its cardioprotective effect against the experimental model of isoprenaline-induced myocardial infarction via MIAT/miR-200a/Nrf2/TXINP pathway.
We explored how lutein (LU) could help protect the heart from damage caused by acute myocardial infarction (AMI). In our research, rats received LU before being induced with heart attack.
We observed that LU treatment reduced markers of heart damage, improved heart function, and showed beneficial changes in various cardiac proteins. However, while these findings are promising, they are based on an experimental model, which means further studies in humans are needed to confirm real-world effectiveness.
2
Lutein supplements show no heart benefit
Effect of long-chain ω-3 fatty acids and lutein + zeaxanthin supplements on cardiovascular outcomes: results of the Age-Related Eye Disease Study 2 (AREDS2) randomized clinical trial.
We aimed to find out if taking lutein and omega-3 supplements could help lower the risk of heart problems in older adults with age-related macular degeneration.
In a large study, over 4,200 participants were randomly assigned to receive either these supplements or a placebo while being monitored for almost five years.
Unfortunately, we found that neither lutein nor the omega-3s made a significant difference in reducing heart attack risk or other cardiovascular issues.
7
Effect of lutein on heart attack
Plasma carotenoids and risk of acute myocardial infarction in the Singapore Chinese Health Study.
This study looked at how specific carotenoids, like lutein, affect the risk of heart attacks. We examined data from 280 heart attack cases and 560 matched controls within a large group of Chinese men and women.
We discovered that higher levels of lutein in the blood could reduce heart attack risk, with promising results showing a significant trend. However, it's important to note that not all carotenoids showed the same benefits. Our findings suggest that lutein could play a cardioprotective role.
4
Carotenoids linked to heart health
Dietary carotenoids and risk of coronary artery disease in women.
We examined the relationship between dietary carotenoids and the risk of coronary artery disease (CAD) in women. In our study, 73,286 female nurses reported their carotenoid intake in 1984 and were followed for 12 years. While we found that higher intakes of beta-carotene and alpha-carotene were linked to a lower risk of CAD, lutein and other carotenoids showed no significant benefit.
This suggests that while certain carotenoids may support heart health, lutein alone might not be effective in reducing heart attack risks.
References
Wang M, Tang R, Zhou R, Qian Y, Di D. The protective effect of serum carotenoids on cardiovascular disease: a cross-sectional study from the general US adult population. Front Nutr. 2023;10:1154239. doi:10.3389/fnut.2023.1154239
Abdelmonem M, Ibrahim SM, Essam RM, Amin HAA, Abd-Elmawla MA. Lutein exerts its cardioprotective effect against the experimental model of isoprenaline-induced myocardial infarction via MIAT/miR-200a/Nrf2/TXINP pathway. J Biochem Mol Toxicol. 2021;35:e22899. doi:10.1002/jbt.22899
Ouyang B, Li Z, Ji X, Huang J, Zhang H, et al. The protective role of lutein on isoproterenol-induced cardiac failure rat model through improving cardiac morphology, antioxidant status via positively regulating Nrf2/HO-1 signalling pathway. Pharm Biol. 2019;57:529. doi:10.1080/13880209.2019.1649436
Bonds DE, Harrington M, Worrall BB, Bertoni AG, Eaton CB, et al. Effect of long-chain ω-3 fatty acids and lutein + zeaxanthin supplements on cardiovascular outcomes: results of the Age-Related Eye Disease Study 2 (AREDS2) randomized clinical trial. JAMA Intern Med. 2014;174:763. doi:10.1001/jamainternmed.2014.328
Koh WP, Yuan JM, Wang R, Lee YP, Lee BL, et al. Plasma carotenoids and risk of acute myocardial infarction in the Singapore Chinese Health Study. Nutr Metab Cardiovasc Dis. 2011;21:685. doi:10.1016/j.numecd.2009.12.005
Osganian SK, Stampfer MJ, Rimm E, Spiegelman D, Manson JE, et al. Dietary carotenoids and risk of coronary artery disease in women. Am J Clin Nutr. 2003;77:1390.